The purpose of the BROADWAY trial (NCT02066103) is to assess the safety and feasibility of local oncological drug delivery into the bronchial wall after recanalization of subjects with malignant airway obstruction. Safety and feasibility (technical success) will be assessed. This localized delivery is intended as an adjunct therapy and all subjects will receive standard of care oncology therapy as determined by their treating physicians. The BROADWAY trial utilizes the Blowfish device. For more information, please contact clinicaltrials@mercatormed.com.